CD38 anticorps (Biotin)

N° du produit ABIN6296644

Cet anticorps Souris Monoclonal détecte spécifiquement CD38 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CD38 anticorps (Biotin) (ABIN6296644)

Antigène: CD38

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD38 est conjugé à/à la Biotin

Application: ELISA

Clone: 1G8-G9-H11

Détail du produit anti-CD38 anticorps (Biotin)

Fonction: Mouse anti CD38 (1G8-G9-H11) [+Biotin] Antibody,

Immunogène: Immunogen was recombinant Human CD38 that derived from E.coli. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA (recommended work dilution= 1:500,000)

Restrictions: For Research Use only

Stockage

Reconstitution: Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution. Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: -20°C

Détails sur CD38

Antigène: CD38

Autre désignation: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Sujet:

Target Description: CD38  (cluster of differentiation  38), also known as  cyclic ADP ribose hydrolase  is a  glycoprotein found on the surface of many immune cells (white blood cells), including  CD4+,  CD8+,  B lymphocytes  andnatural killer cells. CD38 also functions in  cell adhesion,  signal transduction  and  calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. Diseases associated with CD38 include B Cell Prolymphocytic Leukemia and Richter's Syndrome. Among its related pathways are Hematopoietic cell lineage and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. GO annotations related to this gene include transferase activity and hydrolase activity, acting on glycosyl bonds. An important paralog of this gene is BST1.

Gene Symbol: CD38

ID gène: 952

UniProt: P28907